--- doc/manual.tex.orig 2019-04-18 21:03:11 UTC +++ doc/manual.tex @@ -767,8 +767,8 @@ of ``nan"s. The basic usages for linear model association analysis with either the PLINK binary ped format or the BIMBAM format are: \begin{verbatim} -./gemma -bfile [prefix] -lm [num] -o [prefix] -./gemma -g [filename] -p [filename] -a [filename] -lm [num] -o [prefix] +gemma -bfile [prefix] -lm [num] -o [prefix] +gemma -g [filename] -p [filename] -a [filename] -lm [num] -o [prefix] \end{verbatim} where the ``-lm [num]" option specifies which frequentist test to use, @@ -825,8 +825,8 @@ The basic usages to calculate an estimated relatedness either the PLINK binary ped format or the BIMBAM format are: % \begin{verbatim} -./gemma -bfile [prefix] -gk [num] -o [prefix] -./gemma -g [filename] -p [filename] -gk [num] -o [prefix] +gemma -bfile [prefix] -gk [num] -o [prefix] +gemma -g [filename] -p [filename] -gk [num] -o [prefix] \end{verbatim} % where the ``-gk [num]" option specifies which relatedness matrix to @@ -887,8 +887,8 @@ matrix with either the PLINK binary ped format or the are: % \begin{verbatim} -./gemma -bfile [prefix] -k [filename] -eigen -o [prefix] -./gemma -g [filename] -p [filename] -k [filename] -eigen -o [prefix] +gemma -bfile [prefix] -k [filename] -eigen -o [prefix] +gemma -g [filename] -p [filename] -k [filename] -eigen -o [prefix] \end{verbatim} % where the ``-bfile [prefix]" specifies PLINK binary ped file prefix; @@ -923,8 +923,8 @@ The basic usages for association analysis with either ped format or the BIMBAM format are: \begin{verbatim} -./gemma -bfile [prefix] -k [filename] -lmm [num] -o [prefix] -./gemma -g [filename] -p [filename] -a [filename] -k [filename] -lmm [num] -o [prefix] +gemma -bfile [prefix] -k [filename] -lmm [num] -o [prefix] +gemma -g [filename] -p [filename] -a [filename] -k [filename] -lmm [num] -o [prefix] \end{verbatim} where the ``-lmm [num]" option specifies which frequentist test to @@ -1037,8 +1037,8 @@ The basic usages for association analysis with either ped format or the BIMBAM format are: \begin{verbatim} -./gemma -bfile [prefix] -k [filename] -lmm [num] -n [num1] [num2] [num3] -o [prefix] -./gemma -g [filename] -p [filename] -a [filename] -k [filename] -lmm [num] +gemma -bfile [prefix] -k [filename] -lmm [num] -n [num1] [num2] [num3] -o [prefix] +gemma -g [filename] -p [filename] -a [filename] -k [filename] -lmm [num] -n [num1] [num2] [num3] -o [prefix] \end{verbatim} @@ -1069,8 +1069,8 @@ In addition, when a small proportion of phenotypes are missing, one can impute these missing values before association tests: \begin{verbatim} -./gemma -bfile [prefix] -k [filename] -predict -n [num1] [num2] [num3] -o [prefix] -./gemma -g [filename] -p [filename] -a [filename] -k [filename] -predict +gemma -bfile [prefix] -k [filename] -predict -n [num1] [num2] [num3] -o [prefix] +gemma -g [filename] -p [filename] -a [filename] -k [filename] -predict -n [num1] [num2] [num3] -o [prefix] \end{verbatim} @@ -1099,8 +1099,8 @@ The basic usages for fitting a BSLMM with either the P format or the BIMBAM format are: \begin{verbatim} -./gemma -bfile [prefix] -bslmm [num] -o [prefix] -./gemma -g [filename] -p [filename] -a [filename] -bslmm [num] -o [prefix] +gemma -bfile [prefix] -bslmm [num] -o [prefix] +gemma -g [filename] -p [filename] -a [filename] -bslmm [num] -o [prefix] \end{verbatim} where the ``-bslmm [num]" option specifies which model to fit, @@ -1225,9 +1225,9 @@ The basic usages for association analysis with either ped format or the BIMBAM format are: \begin{verbatim} -./gemma -bfile [prefix] -epm [filename] -emu [filename] -ebv [filename] -k [filename] +gemma -bfile [prefix] -epm [filename] -emu [filename] -ebv [filename] -k [filename] -predict [num] -o [prefix] -./gemma -g [filename] -p [filename] -epm [filename] -emu [filename] -ebv [filename] +gemma -g [filename] -p [filename] -epm [filename] -emu [filename] -ebv [filename] -k [filename] -predict [num] -o [prefix] \end{verbatim} @@ -1300,8 +1300,8 @@ The basic usages for variance component estimation wit matrices are: \begin{verbatim} -./gemma -p [filename] -k [filename] -n [num] -vc [num] -o [prefix] -./gemma -p [filename] -mk [filename] -n [num] -vc [num] -o [prefix] +gemma -p [filename] -k [filename] -n [num] -vc [num] -o [prefix] +gemma -p [filename] -mk [filename] -n [num] -vc [num] -o [prefix] \end{verbatim} where the ``-vc [num]" option specifies which estimation to use, in @@ -1349,8 +1349,8 @@ binary ped format or the BIMBAM format. The basic usag component estimation with summary statistics are: \begin{verbatim} -./gemma -beta [filename] -bfile [prefix] -vc 1 -o [prefix] -./gemma -beta [filename] -g [filename] -p [filename] -a [filename] -vc 1 -o [prefix] +gemma -beta [filename] -bfile [prefix] -vc 1 -o [prefix] +gemma -beta [filename] -g [filename] -p [filename] -a [filename] -vc 1 -o [prefix] \end{verbatim} where the ``-vc 1" option specifies to use MQS-HEW; ``-beta @@ -1395,8 +1395,8 @@ previous MQS run. The basic usages for using the asymp compute the confidence intervals are \begin{verbatim} -./gemma -beta [filename] -bfile [prefix] -ref [prefix] -pve [num] -ci 1 -o [prefix] -./gemma -beta [filename] -g [filename] -p [filename] -ref [prefix] -pve [num] -ci 1 -o [prefix] +gemma -beta [filename] -bfile [prefix] -ref [prefix] -pve [num] -ci 1 -o [prefix] +gemma -beta [filename] -g [filename] -p [filename] -ref [prefix] -pve [num] -ci 1 -o [prefix] \end{verbatim} In the above usages, ``-ref [prefix]" specifies the prefix of the